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从1981年1月至1991年12月,我们共收治可手术见期乳腺癌61例,其中术前化疗36例,非术前化疗25例。术前化疗组中,经尺动脉插管给药19例,静脉给药17例,有效率分别为73.7%和76.5%(P>0.05),5年生存率分别为68.4%和70.6%(P>0.05),总有效率和5年生率率分别为75.0%和69.4%。5年生存率明显高于非术前化疗组的36.0%(P<0.05)。结果表明:术前化疗对改善可手术Ⅲ期乳腺癌的预后有其重要的意义。
From January 1981 to December 1991, we treated a total of 61 patients with operable stage breast cancer, including 36 preoperative chemotherapy and 25 non-preoperative chemotherapy. In the preoperative chemotherapy group, 19 patients received catheterization through the ulnar artery and 17 received intravenous administration. The effective rates were 73.7% and 76.5%, respectively (P>0.05). The 5-year survival rate was 68. .4% and 70.6% (P>0.05), and the total effective rate and 5-year rate were 75.0% and 69.4%, respectively. The 5-year survival rate was significantly higher than that of the non-preoperative chemotherapy group (36.0%) (P < 0.05). The results showed that preoperative chemotherapy has important implications for improving the prognosis of operable stage III breast cancer.