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目的研究分析药物干预对减少儿童抗生素相关性腹泻(AAD)的效果。方法选取我院于2009年2月至2012年3月收治的456例儿童呼吸道感染患者的临床资料,进行回顾性分析。对确诊为AAD的213例患者采用药学干预措施。结果抗生素不合理使用是导致儿童AAD出现的主要原因,在药学干预之后,抗生素得到合理使用,AAD发生率降低。结论药学干预可以降低儿童AAD发生概率,提高治疗的效果。
Objective To study the effect of drug intervention on reducing antibiotic-associated diarrhea (AAD) in children. Methods The clinical data of 456 children with respiratory tract infection admitted in our hospital from February 2009 to March 2012 were retrospectively analyzed. Of the 213 patients diagnosed with AAD, pharmacological interventions were used. Results The unreasonable use of antibiotics was the main reason leading to AAD in children. After the intervention, antibiotics were used reasonably and the incidence of AAD was decreased. Conclusion Pharmacological intervention can reduce the incidence of AAD in children and improve the therapeutic effect.