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为了探讨机体免疫反应在幽门螺杆菌（Ｈｐ）致病中的作用，本文检测了１５９例胃十二指肠疾病患者血清中特异性ＨｐＩｇＥ。结果显示约６０％的Ｈｐ感染者可产生抗ＨｐＩｇＥ，并且其与胃粘膜病变严重程度有关。提示血清特异性抗ＨｐＩｇＥ参与了Ｈｐ的致病过程
In order to investigate the role of the immune response in the pathogenesis of Helicobacter pylori (Hp), we examined the specificity of serum HpIgE in 159 patients with gastroduodenal disease. The results show that about 60% of Hp infected patients can produce anti-HpIgE, and it is related to the severity of gastric mucosal lesions. Suggesting that serum-specific anti-HpIgE is involved in the pathogenesis of Hp