从 3种不同血清型的柱状嗜纤维菌中提取菌体脂多糖 (LPS) ,测定了其中蛋白质含量及其成分的变化 ,并分别作为免疫原接种翘嘴鳜 ,对LPS的免疫原性进行了比较。结果表明 ,不同血清型的柱状嗜纤维菌菌体LPS中蛋白质含量没有明显差别 (t测验 ,P >0 .0 5 ) ,而其中蛋白质成分则有明显的血清型特异性。不同血清型的菌体LPS对翘嘴鳜的免疫原性没有明显差别 (t测验 ,P >0 .0 5 ) The lipopolysaccharide (LPS) was extracted from three different serotypes of columnar filamentous bacteria, and the protein content and its components were determined. The immunogenicity of LPS was evaluated by immunizing with LPS Compare The results showed that there was no significant difference in the protein content of LPS from the different serotypes (t test, P> 0.05), but the protein content of the LPS was obviously serotype-specific. There was no significant difference in the immunogenicity of LPS from different serotypes of LPS (t test, P> 0.05)