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肥胖症作为一种能量代谢性疾病,已成为世界范围内的健康问题。肿瘤坏死因子-α(Tumornecrosis factor,TNF-α)是一种多效性细胞因子,在肥胖发生过程中起着非常重要的作用。TNF-α可以通过影响体内糖代谢、脂代谢及炎症反应参与肥胖的发生过程。本文就TNF-α在肥胖的发生过程中的作用做一简要综述。
Obesity as an energy metabolic disease has become a worldwide health problem. Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine that plays a very important role in the development of obesity. TNF-α can participate in the process of obesity by affecting the body’s glucose metabolism, lipid metabolism and inflammatory response. This article gives a brief overview of the role of TNF-α in the pathogenesis of obesity.