现将我国40年来在职业中毒临床研究方面的主要成就简述如下:职业中毒诊断铅中毒在铅中毒防治工作中,一向重视生物监测。70年代陆续引进了尿δ—氨基—γ—酮戊酸(ALA)、尿粪卟啉定量、血ALA 脱水酶(ALA-D)。80年代开展了FEP 测定和用血液荧光计测定锌原卟啉(ZPP)。80年代还开始采用原子吸收光谱法和阳极溶山伏安法测定血铅。很多研究者 Now 40 years in our country in occupational poisoning clinical research major achievements are as follows: Occupational poisoning diagnosis of lead poisoning In the prevention and control of lead poisoning, biological monitoring has always been the emphasis. In the 1970s, urinary δ-amino-γ-keto-valerate (ALA), uremic quantitative porphyrin and ALA-D were also introduced. FEP measurements were performed in the 1980s and zinc protoporphyrin (ZPP) was determined using a blood fluorometer. 80s also began to use atomic absorption spectrometry and anodic dissolution voltammetry determination of blood lead. Many researchers