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目的:回顾性分析脑胶质瘤患者术后常规剂量分割三维适形放疗疗效。方法:38例资料完整的胶质瘤术后患者,接受三维适形放疗,治疗剂量50-60Gy/25-30次/5-6周,2Gy/次。结果:38例患者1、2年总生存率为71%,47.4%;低分级胶质瘤1、2年生存率90.5%,85.7%;高分级胶质瘤1、2年生存率47.1%,17.8%;不良反应发生率为7.9。结论:常规剂量分割三维适形放疗治疗未能提高患者生存率,但不良反应率低。
Objective: To retrospectively analyze the effect of conventional three-dimensional conformal radiotherapy in patients with glioma after surgery. Methods: Thirty-eight patients with complete glioma underwent three-dimensional conformal radiotherapy at doses of 50-60 Gy / 25-30 times / 5-6 weeks and 2Gy / time. RESULTS: The overall survival rates at 1 year and 2 years in 38 patients were 71% and 47.4% respectively. The 1-year and 2-year survival rates were 90.5% and 85.7% in low-grade gliomas, respectively. The 1-year and 2-year survival rates of high grade gliomas were 47.1% 17.8%; adverse reaction rate was 7.9. Conclusion: Conventional dose-divided three-dimensional conformal radiotherapy failed to improve the survival rate of patients, but the adverse reaction rate was low.