创伤性脑损伤(Tmumatic brain injury,TBI)因高致死率和致残率受到极大重视。TBI包括原发性损伤和继发性损伤两部分,其中,继发性损伤主要指TBI后出现脑水肿、脑缺血、进展性出血损伤(progressive hemorrhagic ingury,PHI)等。TBI原发性损伤在暴力损害发生时已经不可改变,具有PHI的颅脑损伤患者预后更差,文献报道PHI患者病死率约为20%~([1]),所以对TBI的治疗更多在于处理TBI后的继发进展性损伤。因此,早期预测 Tmumatic brain injury (TBI) is highly valued for high rates of mortality and morbidity. TBI includes primary injury and secondary injury. Secondary injury mainly refers to cerebral edema, cerebral ischemia and progressive hemorrhagic ingury (PHI) after TBI. The primary injury of TBI is unchangeable in the event of a violent injury. The prognosis of patients with PHI is even worse. The mortality rate in patients with PHI is reported to be about 20% ~ ([1]), so the treatment of TBI is more Secondary progressive damage after TBI treatment. Therefore, the early prediction