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用HAbl8G肝癌mAb通过RT-PCR筛选人HCCCDNA文库,克隆出编码HAbl8G的两个CDNA片段(1.4wb和1.0An),其表达产物HAulSG蛋白分子经实验证明与肿瘤的浸润、扩散有关。IHAb18G结构分析HAbl8G基因全长1.4kb和1.0wb,此两片段的开放读框仅在第128位有差别,1.4kb为TCA(编码丝
The human HCCC DNA library was screened by RT-PCR using HAbl8G hepatocarcinoma mAb, and the two CDNA fragments encoding HAbl8G (1.4wb and 1.0An) were cloned. The expression product HAulSG protein molecule was experimentally proved to be related to tumor invasion and proliferation. IHAb18G structural analysis HAbl8G gene full-length 1.4kb and 1.0wb, the open reading frame of these two fragments only in the 128th position difference, 1.4kb TCA (encoded silk