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目的:探讨鼻窦炎口服液对鼻息肉组织中及鼻腔术后黏膜下嗜酸粒细胞超微结构的影响。方法:12例鼻息肉患者术后分成3组.分别用生理盐水、地塞米松和鼻窦炎口服液冲洗鼻腔,每日2次,连续冲洗4周。鼻息肉组织在鼻窦炎口服液和地塞米松培养液中进行体外细胞培养,7d后取出制备成电镜切片。结果:应用鼻窦炎口服液和地塞米松者,电镜均发现嗜酸粒细胞的超微结构发生退行性变。结论:鼻窦炎口服液对鼻腔黏膜下嗜酸粒细胞有抑制作用。
Objective: To investigate the effect of oral rhinitis on the ultrastructure of submucosal eosinophils in tissues of nasal polyps and nasal cavity. Methods: Twelve patients with nasal polyps were divided into 3 groups after operation. The nasal cavity was rinsed with normal saline, dexamethasone and sinusitis oral solution twice a day for 4 weeks. Nasal polyps were cultured in sinusitis oral solution and dexamethasone culture medium in vitro. After 7 days, they were taken out and prepared for electron microscopy. RESULTS: Using sinusitis oral solution and dexamethasone, electron microscopy showed that the ultrastructure of eosinophils was degenerative. Conclusion: Sinusitis oral solution has inhibitory effect on eosinophils in nasal mucosa.