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本文介绍应用呼吸机治疗6例呼吸窘迫综合征新生儿的临床经验,所有患儿均经胸片确诊。全部病例均在生后30分钟内出现呼吸困难,经治疗后死亡3例。作者认为早期采用持续呼吸道正压(CPAP)治疗可取得良好效果,某些病例仅需治疗4～5小时便可使肺泡扩张稳定。重症患儿因已有明显肺水肿和肺泡上皮细胞坏死脱落,肺顺应性差,CPAP治疗很难奏效,必须应用呼呼机作间歇正压呼吸,作者还推荐对重症患儿延长吸气时间,使吸/呼比例成2:1,不需增加吸气压和氧浓度便可使血氧分压明显提高。
This article describes the application of ventilator in the treatment of 6 cases of respiratory distress syndrome in neonates clinical experience, all children were confirmed by chest X-ray. All cases were breathing difficulties within 30 minutes after birth, died after treatment in 3 cases. Authors believe that early use of continuous positive airway pressure (CPAP) treatment can achieve good results, in some cases only 4 to 5 hours of treatment can be stable alveolar dilation. Severe children with obvious pulmonary edema and alveolar epithelial cell necrosis loss, poor lung compliance, CPAP treatment is difficult to work, you must use the whirring machine intermittent positive pressure breathing, the author also recommended to prolong the inspiratory time in children with severe, so that suction / Call ratio of 2: 1, without increasing inspiratory pressure and oxygen concentration can be significantly increased partial pressure of oxygen.