对鲤鱼、鲫鱼进行了百毒杀 (BESTAQUAM s)的急性毒性试验 ;同时用试管稀释法进行了百毒杀对嗜水气单胞菌 (Aeromonashydrophila)、荧光假单胞菌 (Pseudomonasfluorescens)两种鱼类常见致病菌的抑菌试验。结果表明百毒杀对鲤鱼 2 4h和 48h的半数致死浓度 (LC50 )分别为 7 13mg/L和 6 87mg/L ,安全浓度为 0 6 9mg/L ;鲫鱼 2 4h和 48h的半数致死浓度 (LC50 )分别为 :13 72mg/L和 13 2 2mg/L ,安全浓度 1 32mg/L ;对嗜水气单胞菌(Aeromonashydrophila)和荧光假单胞菌 (Pseudomonasfluorescens)的最低抑菌浓度 (MIC)均为 0 0 1mg/L ,最低杀菌浓度 (MRC)为 0 1mg/L ;通过对中毒死亡鱼的病理组织学观察表明 :百毒杀主要是对鱼类的鳃、肠、肝和肾造成较大的损害 ,特别是对鳃的损害与鱼的死亡有很大的关系。 The carp and crucian carp were subjected to the acute toxicity test of BESTAQUAM s. At the same time, two kinds of fish, Aeromonas hydrophila, Pseudomonas fluorescens, Bacteriostasis test of common pathogenic bacteria. The results showed that the median lethal concentrations (LC50) of the two pesticides against carp at 24 h and 48 h were 7 13 mg / L and 6 87 mg / L respectively, and the safe concentration was 0 6 9 mg / L. The LC50 ) Were 13 72 mg / L and 132 2 mg / L respectively, and the safe concentration was 132 mg / L. The minimum inhibitory concentrations (MICs) against Aeromonas hydrophila and Pseudomonas fluorescens were The lowest bactericidal concentration (MRC) was 0 1 mg / L. The histopathological observation of fish killed by poisoning showed that the poisoning caused by poisoning was mainly caused by the gills, intestines, liver and kidney of fish Of the damage, especially damage to the gills and fish have a great relationship.