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目的 用脂质结合唾液酸 (LSA)与恶性肿瘤特异性生长因子 (TSGF)对肺癌诊断的对比性研究。方法 用改良间苯二酚法和化学比色法 ,同时检测 56例肺癌、65例肺良性疾病、50例健康成人血清中 LSA和 TSGF的含量。结果 在肺癌患者中 ,LSA阳性率为 80 .4% ,诊断正确率为 87.3% ;TSGF阳性率为 85.7% ,诊断正确率为 89.6% ,二者结果相似。33例各型肺癌患者的 LSA和 TSGF水平变化与手术切除疗效相关。结论 LSA及 TSGF对肺癌疗效监测具有较显著的临床意义。尤其是联合使用 LSA和 TSGF检测用于提高临床肺癌的正确诊断率更具有价值
Objective To compare the diagnosis of lung cancer with lipid-associated sialic acid (LSA) and malignant tumor-specific growth factor (TSGF). Methods The contents of LSA and TSGF in serum of 56 patients with lung cancer, 65 patients with benign lung diseases and 50 healthy adults were detected by modified resorcinol method and chemical colorimetry. Results Among lung cancer patients, the positive rate of LSA was 80.4%, the diagnostic accuracy rate was 87.3%, the positive rate of TSGF was 85.7%, and the diagnostic accuracy rate was 89.6%. The results were similar. The changes of LSA and TSGF levels in 33 lung cancer patients were related to the curative effect. Conclusion LSA and TSGF have significant clinical significance in monitoring the curative effect of lung cancer. Especially the combined use of LSA and TSGF detection is more valuable for improving the correct diagnosis rate of clinical lung cancer