论文部分内容阅读
目的对头孢哌酮钠的不良反应发生情况进行分析,为临床合理用药提供有力依据。方法收集本市药品不良反应监测中心收集的77例头孢哌酮钠不良反应事件报告,对不良反应发生情况进行统计分析。结果不良反应患者男女比例为1.33∶1,其中以0~10岁患儿占比最高,为27.3%;其次为>60岁患者,占比为18.2%;大部分患者为1次/d静脉给药,不良反应多发生于用药后30 min;患者不良反应以过敏反应为主,同时还有部分胃肠道反应,原有疾病为呼吸系统疾病与消化系统疾病。结论头孢哌酮钠易引发皮疹、药物热等过敏反应与轻微胃肠道反应,在临床中应用时应持续监测不良反应发生情况,促使临床合理用药水平不断提高。
Objective To analyze the occurrence of adverse reactions of cefoperazone sodium and provide a strong basis for clinical rational drug use. Methods A total of 77 cases of cefoperazone sodium adverse reactions were collected from adverse drug reaction monitoring center in our city, and the incidence of adverse reactions were statistically analyzed. Results The proportion of male patients to female patients was 1.33:1, with the highest proportion of children aged 0-10 years (27.3%), followed by those aged> 60 years (18.2%). Most patients were given once / d intravenous Drugs, adverse reactions occurred in the treatment of 30 min; adverse reactions in patients with allergic reactions, but also some gastrointestinal reactions, the original diseases of respiratory diseases and digestive diseases. Conclusion Cefoperazone sodium can cause allergic reactions such as skin rash, drug fever and mild gastrointestinal reactions. It should be continuously monitored in the clinical application of adverse reactions, and promote the rational use of drugs in clinical practice.