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13-顺维甲酸(i sotretinoin)常用于治疗痤疮。治疗中眼部问题是已充分认识的并发症。评价此时戴接触眼镜所遇到的眼部问题,以便从治疗开始前即建立咨询指导。在用13-顺维甲酸(1mg/kg/d)治疗的16周期间及以后,共观察了157例患者,询问了特殊的眼部症状,包括干眼症、红眼症、瘙痒、眼部结痂/粘着、畏光、视力模糊。每6～8周嘱患者复诊,检查其眼部症状。结果,1组戴接触眼镜的11例,2组不戴接触眼镜的146例,其眼部合并症的发生率为(1)干眼症:1组7例(64%),2组41例(28%),两组比较,有显著性差异(P=0.05)发生
13-retinoic acid (i sotretinoin) commonly used in the treatment of acne. Eye treatment is a well-recognized complication. Evaluate the eye problems encountered with contact lenses at this time to establish counseling prior to the start of treatment. A total of 157 patients were observed during and after 16 weeks of treatment with 13-cis-retinoic acid (1 mg / kg / d) and asked for specific ocular symptoms including dry eye, red eye, pruritus, ocular nodules Scab / sticking, photophobia, blurred vision. Zhu Huanzhe every 6 to 8 weeks referral, check the ocular symptoms. Results: One group of 11 patients wearing contact lenses and two group of 146 patients without contact lenses had ocular complications (1) dry eye: 7 cases (64%) in group 1, 41 cases in 2 groups (28%). There was a significant difference (P = 0.05) between the two groups