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目的探讨重症肺炎支原体肺炎(MPP)患儿临床特征及联合治疗方法。方法回顾性分析23例重症MPP临床特征、实验室指标、X线胸片特征、诊治过程及临床疗效。结果 23例均有高热、咳嗽,入院前病程7～12d。18例(78.3%)白细胞升高,C反应蛋白、血沉和乳酸脱氢酶均明显增高;15例(65.2%)X线胸片表现为一侧肺部片状阴影者8例(34.8%)见双侧阴影,合并胸腔积液10例(43.5%)。17例(73.9%)在治疗3周内痊愈,6例(26.1%)在1个月内痊愈。结论儿童重症MPP有其特殊临床表现,应早期识别,并及时给予大环内酯类抗生素,联合应用广谱抗生素及肾上腺皮质激素等治疗可取得良效。
Objective To investigate the clinical features and treatment of severe Mycoplasma pneumoniae pneumonia (MPP) in children. Methods Retrospective analysis of 23 cases of severe MPP clinical features, laboratory parameters, chest X-ray features, diagnosis and treatment process and clinical efficacy. Results All 23 cases had fever and cough, and the course of disease was 7-12 days before admission. Eighteen cases (78.3%) had leukocytosis, C-reactive protein, erythrocyte sedimentation rate and lactate dehydrogenase were significantly increased; 15 cases (65.2%) X-ray showed one side of the lung flake shadow in 8 cases (34.8% See bilateral shadows, combined pleural effusion in 10 cases (43.5%). Seven patients (73.9%) recovered within 3 weeks of treatment and 6 (26.1%) recovered within 1 month. Conclusion Severe MPP in children has its special clinical manifestations, should be identified early and timely macrolide antibiotics, combined with broad-spectrum antibiotics and adrenal cortex hormones and other treatment can be good.