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目的：探讨腰椎穿刺脑脊液置换疗法治疗蛛网膜下腔出血（ＳＡＨ）的临床疗效。方法：采用腰椎穿刺脑脊液置换疗法治疗继发性ＳＡＨ３１例（治疗组）和原发性ＳＡＨ２９例（对照组），间隔２～３日置换１次，可置换２～５次。结果：治疗组总有效率（９０．３％）与对照组总有效率（９３．１％）比较无显著性差异（χ２＝０．１５，Ｐ＞０．０５）。结论：腰椎穿刺脑脊液置换疗法能降低原发性ＳＡＨ和继发性ＳＡＨ的颅内压，改善脑脊液循环，清除脑血管内活性物质，防止脑血管痉挛，减少蛛网膜粘连，降低病死率，且未见脑疝及其他不良反应
Objective: To investigate the clinical effect of lumbar puncture and cerebrospinal fluid replacement therapy on patients with subarachnoid hemorrhage (SAH). Methods: Thirty - six cases of secondary SAH (treatment group) and 29 cases of primary SAH (control group) were treated with lumbar puncture and cerebrospinal fluid replacement therapy. The patients were replaced one to two times every two to three days and replaced 2 to 5 times. Results: The total effective rate (90.3%) in the treatment group was not significantly different from that in the control group (93.1%) (χ2 = 0.15, P> 0.05). Conclusion: Lumbar puncture and cerebrospinal fluid replacement therapy can reduce intracranial pressure of primary SAH and secondary SAH, improve cerebrospinal fluid circulation, clear cerebral vascular active substances, prevent cerebral vasospasm, reduce arachnoid adhesions and reduce mortality rate See hernia and other adverse reactions