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总结了文献报道的甲磺胺磺隆及其中间体的合成工艺路线和具体的合成方法。甲磺胺磺隆是由4-氰基甲苯或关键中间体N-叔丁基-2-甲氧羰基-5-甲基苯磺酰胺为原料经多步反应得到产品,主要有2条工艺路线。
The synthesis route and specific synthesis methods of metsulfuron - methyl and its intermediates reported in the literature are summarized. Sulfasulfomethazine is obtained from 4-cyanotoluene or key intermediate N-tert-butyl-2-methoxycarbonyl-5-methylbenzenesulfonamide as raw materials through multi-step reaction. There are mainly 2 routes.