人的生殖效率似乎很低,据最近各种报告,大约有50～70％的受精卵夭折。但一般认为,临床上自然流产率是15～20％。妊娠初期的流产中,其重要原因是遗传的或偶然的染色体异常。作为习惯性流产的原因,以往认为:①子宫异常,②内分泌异常,③感染,④夫妇染色体异常。关于这四个原因,最近4年来,名古屋市立大学医院对334名习惯性流产者进行了统计分析,其结果:①占12.3％,②占13.7％,③占1.9％,④占4.5％。而①～④之外的所谓原因不明的反复流产是67.6％,其中,有相当比例是免疫学因素所致。其机理:A.母体内对胎儿拒绝排斥反应的抑制因子不充分。B.母体内 Reproductive efficiency appears to be low, according to recent reports that about 50 to 70% of fertilized eggs die. But generally believed that the clinical spontaneous abortion rate is 15 ~ 20%. Abortion in early pregnancy, the important reason is genetic or accidental chromosomal abnormalities. As a habitual abortion, in the past that: ① uterine abnormalities, ② endocrine abnormalities, ③ infection, ④ couples chromosomal abnormalities. For these four reasons, the Nagoya City University Hospital conducted a statistical analysis of 334 habitual abortion patients over the last four years. The results showed that: ① 12.3%, ② 13.7%, ③ 1.9%, ④ 4.5%. The so-called unexplained recurrent miscarriage outside ① ~ ④ was 67.6%, of which a considerable proportion was caused by immunological factors. The mechanism: A. maternal rejection rejection of the fetus of the inhibitory factor is not sufficient. B. within the mother