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目的分析1997～2004年山东省眼库角膜供体的临床应用情况。设计回顾性病例系列研究。研究对象3475个角膜供体。方法分析角膜供体应用于患者的年龄、区域、手术方式及疾病种类。主要指标术式及疾病种类结果接受角膜供体多为中年(44.7%)及青年(32.5%)患者。80.4%患者来自山东省。供体分别用于穿透性角膜移植术2376例,板层角膜移植术984例,角膜表面镜片术115例。应用于感染性角膜炎(49.4%)、圆锥角膜(13.8%)、角膜白斑(9.7%)、大泡性角膜病变(8.7%)等眼病。在感染性角膜炎中,真菌性角膜炎占39.0%,病毒性角膜炎占35.2%,细菌性角膜炎占21.9%。结论感染性角膜炎是山东省眼库角膜供体应用最多的疾病,其次为圆锥角膜。角膜白斑与大泡性角膜病变分别居于第三、四位。
Objective To analyze the clinical application of corneal donors in Shandong Province from 1997 to 2004. Design retrospective case series. Study target 3475 corneal donors. Methods The corneal donor was analyzed for age, region, operation method and disease type. The main indicators of surgical procedures and types of disease results to accept corneal donors were mostly middle-aged (44.7%) and young patients (32.5%). 80.4% patients came from Shandong Province. Donors were used for penetrating keratoplasty in 2376 cases, lamellar keratoplasty in 984 cases, 115 cases of corneal surface ophthalmoscopy. For infectious keratitis (49.4%), keratoconus (13.8%), corneal leukoplakia (9.7%), bullous keratopathy (8.7%) and other eye diseases. In infectious keratitis, fungal keratitis accounted for 39.0%, viral keratitis accounted for 35.2%, bacterial keratitis accounted for 21.9%. Conclusion Infectious keratitis is the most widely used corneal donor in Shandong Province, followed by keratoconus. Leukoplakia and bullous keratopathy were the third and fourth.