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目的探究无创正压呼吸机辅助通气治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭疗效观察。方法选取新乡市中心医院收治的56例COPD合并Ⅱ型呼吸衰竭患者,随机分为常规组与观察组各28例。常规组予以常规综合治疗,观察组在常规组基础上予以无创正压呼吸机辅助通气治疗。统计两组患者治疗前后血气分析指标、临床效果及不良反应发生情况。结果治疗3d后,观察组p H值与常规组相比,差异无统计学意义(P>0.05),观察组动脉血氧分压、动脉血二氧化碳分压优于常规组,差异有统计学意义(P<0.05);观察组临床效果高于常规组,两组差异有统计学意义(P<0.05)。结论对COPD合并Ⅱ型呼吸衰竭患者予以无创正压呼吸机辅助通气治疗,可显著提高其治疗效果,且安全性较高,在临床治疗中具有重要意义。
Objective To investigate the curative effect of noninvasive positive pressure ventilator assisted ventilation on chronic obstructive pulmonary disease (COPD) complicated with type Ⅱ respiratory failure. Methods Fifty-six patients with COPD and type Ⅱ respiratory failure admitted to Xinxiang Central Hospital were randomly divided into routine treatment group and observation group with 28 cases each. The conventional group was given conventional comprehensive treatment. The observation group was given non-invasive positive pressure ventilator assisted ventilation on the basis of the conventional group. Statistics before and after treatment of two groups of patients blood gas analysis indicators, clinical effects and adverse reactions. Results After 3 days of treatment, there was no significant difference in p H between observation group and control group (P> 0.05). The partial pressure of arterial oxygen and arterial partial pressure of carbon dioxide in observation group were better than those in control group (P <0.05). The clinical effect of the observation group was higher than that of the conventional group, the difference between the two groups was statistically significant (P <0.05). Conclusion Noninvasive positive pressure ventilator-assisted ventilation is a safe and effective way to improve COPD patients with type Ⅱ respiratory failure. It is of great significance in clinical treatment.