乙胺丁醇(EB)是六十年代开发的一种结核病化疗药物,过去认为EB是一较安全的药物,随着近年临床的广泛应用,其不良反应已引起人们的日益重视。一、视神经损害 EB最重要的不良反应是对视神经损害,严重者可发生难以逆转的视神经炎,表现为视物模糊,视力减退,视野缺损、视敏度减低和识别绿色能力丧失。反应发生率与使用EB的剂量成正比,并与服药期限有密切关系。文献报道,每日服EB50mg/kg,25mg/kg和15mg/kg的患者中,发 Ethambutol (EB) was developed in the 1960s as a tuberculosis chemotherapy drug. In the past, EB was regarded as a safer drug. With the wide application in clinic in recent years, its adverse reactions have attracted more and more attention. First, the most important adverse reaction of optic nerve damage EB is damage to the optic nerve, severe reversible optic neuritis can occur, manifested as blurred vision, vision loss, visual field defects, decreased visual acuity and identify the loss of green ability. The incidence of the reaction with the dose of EB is proportional to, and with the duration of medication are closely related. Reported in the literature, daily EB50mg / kg, 25mg / kg and 15mg / kg of patients, hair