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1976年7月,在费城的美国退伍军人会议的代表中,爆发了严重肺炎,引起了医学界和公众的重视。两年后,在军团病的国际讨论会上已证实嗜肺性军团病杆菌是北美和欧洲各地的肺炎同一的病原体。1977年在洛杉矶一所新医院开业后两周就看到第一批军团病。在以后14个月里确诊为此病者49例。仅在1980年3月就确诊了22例。饮用水被认为是嗜肺性军团病杆菌的储存所。在北美和欧洲几所医院出现了此病的流行。在人群中对嗜肺性军团病杆菌抗体的血清学筛选检查显示有不同的类型,在诺丁罕,从健康受试者获得了2023份血清,应用甲醛灭活的卵黄囊抗原,通过间接荧光抗体法检查显示仅有31份(1.5%)具有可检出的抗体。但在俄亥俄,从588名健康人的血清标本中查到有20%的标本,具有对热灭活的嗜肺性军团病杆菌抗原的抗体滴度为1:128或更高。根据肺炎患者所贮存的血清检查的回顾性研究提示,军团病是散
In July 1976, a serious pneumonia broke out among representatives of the U.S. Veterans Convention in Philadelphia, attracting much attention from the medical community and the general public. Two years later, Legionella pneumophila has been shown to be the same pathogen of pneumonia in North America and Europe at an international symposium on Legionnaires’ disease. The first batch of Legionnaires’ Disease was seen two weeks after opening a new hospital in Los Angeles in 1977. In the next 14 months diagnosed as 49 patients with this disease. Only 22 cases were diagnosed in March 1980. Drinking water is considered a reservoir of Legionella pneumophila. The disease has been circulating in several hospitals in North America and Europe. Serological screening tests of V. parahaemolyticus antibodies in the human population showed a different type, with 2023 serums obtained from healthy subjects in Nottingham, formalin-inactivated yolk sac antigen, and indirect fluorescence Antibody method tests revealed that only 31 (1.5%) had detectable antibodies. However, in Ohio, 20% of the samples from 588 healthy human serum samples were found to have an antibody titer of 1: 128 or greater for heat-inactivated Legionella pneumophila antigens. A retrospective study based on the serum tests stored in patients with pneumonia suggests that Legionnaires’ disease is fragmented