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本文通过834例原发性肝癌(PHC)资料分析,探讨高发区PHC发病高峰年龄的特点。结果表明:有HBV感染、家族肿瘤史的男性PHC发病高峰年龄提早到30—49岁,(占总例数的58.39%),均较相应的对照组及文献报道显著提前1—2个年龄组,(P<0.05—0.01),且家族肿瘤史可促使HBV阳性PHC发病高峰年龄提前到30—39岁,提示HBV感染与家族肿瘤史、性别是导致PHC高发和早发的主要因素,也是肝癌高发区重要的流行特征;对上述人群应视为PHC预防重点,其中30—49岁男性更为肝癌的最高危险人群,要加强随访,以期早诊早治。
This article through 834 cases of primary liver cancer (PHC) data analysis to explore the characteristics of the peak incidence of PHC in high incidence areas. The results showed that the peak age of PHC in men with HBV infection and family history of tumors was as early as 30-49 years (58.39% of the total cases), which was significantly earlier than the corresponding control group and the literature reported 1-2 age groups. (P<0.05-0.01), and the family history of tumors can prompt the peak age of HBV-positive PHC to reach the age of 30-39 years, suggesting that HBV infection and family history, gender is the main factor leading to high and premature PHC, and also liver cancer Important epidemic features of high-incidence areas; the above-mentioned population should be regarded as the focus of PHC prevention, among which the 30-49-year-old male is the highest risk group for liver cancer, and follow-ups should be intensified for early diagnosis and early treatment.