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艾滋病(AIDS)的诊断及治疗已经取得了重大的进展.实验室检查可以评价人类免疫缺陷病毒(HIV)感染,包括检HIV-1抗体,直接检测病毒、鉴定替代标记和外周血单个核细胞的表型分析.临床医生对肿瘤、条件致病菌感染、AIDS本身及与其并发症的治疗方面取得了很大的进展.在选择的病人中采用α-干扰素(HFN-α)治疗AIDS相关的Kaposi肉瘤(KS)已经取得了成功.用造血生长因子治疗AIDS引起的白细胞减少和贫血,结果患者白细胞数增加,红细胞输入的需要量减少.除叠氮胸苷(AZT)以外还有数种抗逆转录病毒药物,包括双脱氧胞苷(ddC)、双脱氧肌苷(ddI)、可溶性CD4和糖苷酶抑制剂N-J基脱氧野尻霉素均正在试验中.
Significant advances have been made in the diagnosis and treatment of AIDS, which can be used to assess human immunodeficiency virus (HIV) infections, including HIV-1 antibodies, direct virus detection, identification of surrogate markers and peripheral blood mononuclear cells Phenotypic Analysis Clinicians have made great advances in the treatment of tumors, opportunistic infections, AIDS itself, and its complications, and the use of interferon alpha (HFN-α) in selected patients to treat AIDS-related Kaposi’s sarcoma (KS) has been successful with hematopoietic growth factors in the treatment of AIDS-induced leukopenia and anemia resulting in an increased leucocyte count and a reduced need for red blood cell transfusions Several anti-retroviral strategies in addition to azidothymidine (AZT) Vaccine drugs, including dideoxycytidine (ddC), dideoxyinosine (ddI), soluble CD4 and glycosidase inhibitor NJ-deoxynojirimycin are under test.