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目的:观察促排卵中药调周汤联合氯米芬治疗排卵障碍性不孕的疗效。方法:将112例排卵障碍性不孕患者,随机分为中药调周汤联合氯米芬组(治疗组)60例,氯米芬组(对照组)52例,治疗2个疗程后用B超监测排卵及子宫内膜厚度和受孕情况,停药后继续随访3个月再统计2组受孕情况。结果:治疗组优势卵泡直径明显大于对照组,排卵期子宫内膜较治疗前明显增厚(P<0.05),对照组子宫内膜治疗前后无明显差异(P>0.05)。治疗组与对照组两组治疗2个疗程及随访3个月妊娠率比较有显著差异(P<0.05)。结论:中药调周汤联合氯米芬治疗排卵障碍性不孕,疗效优于单纯用氯米芬。
OBJECTIVE: To observe the curative effect of ovulation-promoting traditional Chinese medicine combined with clomiphene in treating ovulatory dysplasia. Methods: One hundred and twelve cases of ovulation disorder infertility were randomly divided into two groups: control group (60 cases) and clomiphene group (control group). Twenty-two cases were treated with B-mode ultrasound Ovulation and endometrial thickness and pregnancy status were monitored. After stopping the treatment, the patients were followed up for 3 months and then two groups were enrolled. Results: The diameter of dominant follicles in the treatment group was significantly larger than that in the control group. The ovulation endometrium was significantly thicker than that before treatment (P <0.05). There was no significant difference between the control group and the endometrium before and after treatment (P> 0.05). The treatment group and control group two groups of treatment and follow-up of 3 months pregnancy rate was significantly different (P <0.05). Conclusion: Traditional Chinese medicine Zhouzhitang combined with clomiphene in treatment of ovulation failure infertility, curative effect is better than clomiphene alone.