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目的研究克雷白杆菌在小儿急性下呼吸道感染中发病情况及临床特点 ,如何选择抗生素。方法对痰培养克雷白杆菌生长的 2 9例患儿的临床资料、痰培养及其药物敏感实验进行分析。结果克雷白杆菌肺炎在新生儿、婴儿发病率明显高于其他儿童 ,其最主要的特点是痰液粘稠堵塞气道引起呼吸困难。体外药物敏感试验显示 ,克雷白杆菌生长对头孢类抗生素耐药率逐年上升。结论克雷白杆菌已成为小儿下呼吸道感染的不可忽视的致病因素 ,耐药菌株增加成为治疗中难关。依据病原学检测及药敏试验选择用药可减少克雷白杆菌感染及耐药菌株出现。
Objective To study the incidence of Klebsiella bacilli in children with acute lower respiratory tract infection and clinical features, how to choose antibiotics. Methods The clinical data, sputum culture and drug susceptibility test of 29 cases of Klebsiella pneumoniae growing in sputum were analyzed. Results Klebsiella pneumonia in neonates, infants incidence was significantly higher than other children, the most important feature is the mucus clogging the airway caused by breathing difficulties. In vitro drug susceptibility testing showed that the rate of resistance to cephalosporin antibiotics was increasing year by year. Conclusion Klebsiella has become a non-negligible risk factor for pediatric lower respiratory tract infection, and the increase of drug-resistant strains has become a difficult problem in treatment. Based on the etiological test and drug susceptibility testing choose medication can reduce Klebsiella infection and drug-resistant strains appear.