病毒性乙型肝炎(乙肝)是一种危害极大的传染病。乙肝病毒(HBV)感染者在进行辅助生殖技术(ART)助孕人群中的比例正不断增加,在ART实验室中HBV可经精子和卵母细胞由亲代遗传性传播给子代,也可以因水平传播导致其他正常的配子和胚胎感染。高度警惕HBV的传染途径,对健康亲代进行免疫预防,对有传染性的标本进行洗涤,加强实验室安全管理,施行亚甲蓝光化学法灭活病毒等相应阻断措施,是安全进行ART的必要保证。 Viral hepatitis B (hepatitis B) is a potentially devastating infectious disease. The proportion of people living with HBV who are assisted in assisted reproductive technology (ART) is on the increase. HBV can be transmitted from offspring to progeny via sperm and oocyte in ART labs, Horizontal transmission leads to other normal gametes and embryo infections. Highly vigilant HBV infection, immunocompromised healthy parents, washing of infected specimens, strengthening laboratory safety management, and implementing corresponding blocking measures such as inactivation of virus by methylene blue photochemistry are necessary for safe ART Guarantee.