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目的比较米非司酮、乳酸依沙吖啶联合用于中期妊娠引产及单独使用乳酸依沙吖啶终止中期妊娠的效果。方法将54例妊娠15~28周自愿要求引产的患者随机分为观察组(米非司酮联合乳酸依沙吖啶)27例和对照组(单独使用乳酸依沙吖啶)27例,观察两组的宫缩发动、引产所需时间、总产程时间、胎盘胎膜残留情况及产后出血量等情况。结果观察组宫缩发动早、引产所需时间、总产程时间较对照组缩短,胎盘、胎膜残留率低,统计学分析有显著性差异。结论米非司酮联合乳酸依沙吖啶用于中期妊娠引产,方法安全、简便,缩短引产时间,有利于产程进展,对出血量无明显影响,是中期妊娠引产较理想的方法,值得在临床上推广应用。
Objective To compare the effects of mifepristone and ethacridine combined with midazolam in the induction of labor in the second trimester and the use of lamivudine alone in the termination of the second trimester pregnancy. Methods Fifty-four patients who volunteered for induction of labor at 15-28 weeks gestation were randomly divided into observation group (mifepristone combined with ethacridine lactate) and observation group (n = 27) and control group (n = 27) Group contractions mobilization, induction of labor required time, total labor time, residual placental membranes and postpartum hemorrhage and so on. Results In the observation group, the time needed to initiate early labor and induced labor and the duration of induced labor were shorter than those in the control group. The residual rate of the placenta and fetal membranes was low, and the statistical analysis showed significant differences. Conclusions Mifepristone combined with ethacridine lactate is suitable for mid-term pregnancy induction. The method is safe, simple and shorten the time of induction of labor, is conducive to the progress of labor and has no significant effect on the amount of bleeding. It is an ideal method for induction of labor during mid-term pregnancy and is worthy of clinical application On the promotion of application.