临床上需要一种客观的方法评价口腔上皮癌前病变,并需要可靠的标志物预测这些病变是否恶变。 本实验对20例口腔高危区,即舌和口底区上皮异常增生的细胞增殖进行了研究。 材料和方法 常规活检取材,标本分作两部分:一半放在BrdU中孵育15 min后按Thornton等方法 Clinically, there is a need for an objective method of evaluating oral precancerous lesions and the need for reliable markers to predict whether these lesions are malignant. In this study, 20 cases of high-risk oral area, that is, tongue and mouth epithelial cell proliferation of epithelial dysplasia were studied. Materials and Methods Conventional biopsy specimens were divided into two parts: half in BrdU incubated for 15 min and then Thornton and other methods