论文部分内容阅读
目的探讨自体血回输对骨水泥型全髋关节置换患者凝血功能的影响。方法将我院2010年3月至2015年3月间收治的100例择期行骨水泥型全髋关节置换术患者随机分为两组,每组50例。其中观察组给予自体血回输,对照组给予异体血输注,比较两组患者血常规、凝血功能变化情况。结果观察组未输异体血比例占到82.00%,明显高于对照组,观察组输异体血量为(65.4±7.3)ml,明显低于对照组(P<0.01);两组术后1 d血常规指标Hb、Hct、PLT均有明显下降(P<0.01),但术后6 d回升,且与术前比较无统计学差异(P>0.05);两组术后1 d凝血指标PT、APTT均较治疗前有明显上升,FIB有明显下降(P<0.05),但均在凝血功能正常范围内,术后6 d凝血指标APTT回降至术前水平。结论骨水泥型全髋关节置换术中自体血回输是一种有效且安全的节约用血的方法,与异体血输注比较血常规及凝血功能无显著差异,值得临床推广应用。
Objective To investigate the effect of autologous blood transfusion on the coagulation function in patients with total hip arthroplasty. Methods 100 patients undergoing total hip arthroplasty in our hospital from March 2010 to March 2015 were randomly divided into two groups (n = 50 in each group). The observation group was given autologous blood transfusion, while the control group was given allogeneic blood transfusion. The blood and coagulation changes were compared between the two groups. Results The proportion of non-transfused blood in the observation group accounted for 82.00%, which was significantly higher than that in the control group (65.4 ± 7.3) ml, which was significantly lower than that in the control group (P <0.01) Hb, Hct and PLT were significantly decreased (P <0.01), but returned to the 6th day after operation, and there was no significant difference compared with that before operation (P> 0.05). The coagulation indexes PT, APTT were significantly higher than before treatment, FIB was significantly decreased (P <0.05), but were within the normal range of coagulation, coagulation index APTT 6 d after surgery back to preoperative levels. Conclusion Autologous blood transfusion in patients with total hip arthroplasty is an effective and safe way to save blood. Compared with allogeneic blood transfusion, there is no significant difference between blood and coagulation, which is worthy of clinical application.