粘膜免疫系统与系统免疫在许多方面都大不相同 ,其重要功能和独特性质成为免疫学研究的热点 ;趋化性细胞因子及其受体参与细胞的生长、发育、分化、凋亡、肿瘤转移、炎症等多种生理和病理过程。粘膜相关趋化性细胞因子在粘膜上皮细胞分化发育及创伤愈合、粘膜淋巴细胞归巢并定居于粘膜特定部位、粘膜急慢性炎症、HIV感染等生理病理过程中起重要作用 ,对研究粘膜免疫系统的特殊功能和独特性质具有重要意义。 Mucosal immune system and immune system in many ways are very different, its important function and unique nature of immunology research has become a hot spot; Chemotactic cytokines and their receptors involved in cell growth, development, differentiation, apoptosis, tumor metastasis , Inflammation and other physiological and pathological processes. Mucosal-related chemotactic cytokines play an important role in the process of mucosal epithelial cell differentiation and wound healing, mucosal lymphocyte homing and colonizing specific parts of the mucous membrane, acute and chronic mucosal inflammation, HIV infection and other physiological and pathological processes. The special features and unique properties of great significance.