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目的分析临床应用阿奇霉素治疗肺炎支原体肺炎的疗程及效果。方法 50例肺炎支原体肺炎患儿,根据随机数字表法分为研究组和对照组,各25例。对照组患儿给予阿奇霉素5 d短疗程治疗,研究组患儿给予阿奇霉素7 d长疗程治疗。分析对比两组患儿临床疗效。结果研究组患儿经阿奇霉素7 d长疗程治疗后,临床总有效率为92.0%,对照组总有效率为68.0%,两组比较差异具有统计学意义(P<0.05);研究组咳嗽消失时间、退热时间、肺部啰音消失时间、住院时间分别为(7.12±2.81)min、(2.15±0.13)min、(5.31±0.57)min、(9.50±1.92)d,均显著优于对照组的(12.57±2.24)min、(4.56±1.32)min、(9.14±0.43)min、(18.40±2.36)d,差异有统计学意义(P<0.05)。结论在临床对肺炎支原体肺炎患儿治疗中,应用阿奇霉素7 d长疗程治疗,可缩短咳嗽消失时间与治疗时间,相较于短疗程治疗可提升临床疗效,发挥积极治疗效果。
Objective To analyze the clinical course and effect of azithromycin in the treatment of Mycoplasma pneumoniae pneumonia. Methods Fifty children with Mycoplasma pneumoniae pneumonia were divided into study group and control group according to the random number table method, with 25 cases each. The control group received azithromycin for 5 days and the study group received azithromycin for 7 days. Analysis and comparison of two groups of children clinical efficacy. Results After treatment with azithromycin for 7 days, the total clinical effective rate was 92.0% in the study group and 68.0% in the control group. The difference between the two groups was statistically significant (P <0.05). The cough disappearing time (7.12 ± 2.81) min, (2.15 ± 0.13) min, (5.31 ± 0.57) min, (9.50 ± 1.92) d, respectively, were significantly better than those in the control group (12.57 ± 2.24) min, (4.56 ± 1.32) min, (9.14 ± 0.43) min and (18.40 ± 2.36) d, respectively. The difference was statistically significant (P <0.05). Conclusions In the clinical treatment of children with Mycoplasma pneumoniae pneumonia, the application of azithromycin for 7 days can shorten the time and duration of cough disappearance, which can improve the clinical curative effect and exert positive curative effect compared with the short course of treatment.