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目的探讨肝素治疗新生儿红细胞增多症-高粘滞度综合征的安全性与有效性。方法观察本院2003-2007年收治的68例诊断为红细胞增多症-高粘滞度综合征的新生儿,对其胆红素、血气分析、血糖、凝血四项,头颅B超进行监测,随机分为肝素治疗组和对照组。结果两组HCT、血红蛋白对比P<0.01,差异有统计学意义。结论肝素能有效降低红细胞增多症引起的高粘滞血症,对减少多器官功能损害是有效的。
Objective To investigate the safety and efficacy of heparin in the treatment of neonatal polycythemia - hyperviscosity syndrome. Methods 68 newborns diagnosed as polycythemia - hyperviscosity syndrome in our hospital from 2003 to 2007 were observed and their bilirubin, blood gas analysis, blood sugar, blood coagulation and cranial ultrasound were monitored randomly Divided into heparin treatment group and control group. Results HCT and hemoglobin in the two groups were significantly different (P <0.01), the difference was statistically significant. Conclusion Heparin can effectively reduce hyperviscosity caused by polycythemia, is effective in reducing multiple organ dysfunction.