论文部分内容阅读
目的了解福建省妇幼保健院2012年住院的手足口病(HFMD)患儿肠道病毒EV71型(EV71)感染情况,为制订防控策略提供依据。方法采集住院患儿血标本共509份(普通病例445份,重症病例64份)进行EV71IgM检测。结果EV71IgM阳性率50.5%(257/509),其中男性49.0%(166/339),女性53.5%(91/170),男女检出率类似。EV71检出率以5~6岁组最高(69.2%),其次2、3岁组(55.0%、61.0%),<1岁最低(37.7%)。全年均有病例发生,2月份检出率最高(85.7%),9月份最低(14.3%)。重症患儿EV71型检出率95.0%,普通病例仅44.0%。结论 2012年住院的HFMD患儿以EV71型感染为主(50.5%),分布具有明显季节和年龄分布特征,应结合季节变化特点加强重点人群的防控。
Objective To understand the infection status of enterovirus EV71 (EV71) in children with HFMD who were hospitalized in Fujian Provincial MCH in 2012, so as to provide basis for the prevention and control strategies. Methods A total of 509 blood samples were collected from hospitalized children (445 common cases and 64 severe cases) for EV71IgM. Results The positive rate of EV71 IgG was 50.5% (257/509), of which 49.0% (166/339) were male and 53.5% (91/170) were female. The detection rate was similar between men and women. The detection rate of EV71 was the highest (69.2%) in the age group of 5 to 6 years, followed by the age of 2 and 3 (55.0%, 61.0%) and the lowest in the age of 1 (37.7%). Cases occurred throughout the year, the highest detection rate in February (85.7%), the lowest in September (14.3%). In severe children, the detection rate of EV71 was 95.0%, only 44.0% of the common cases. Conclusion In 2012, HFMD was predominant in EV71 infection (50.5%), and the distribution was obviously seasonal and age distribution. The prevention and control of key population should be strengthened according to the seasonal variation.