Background::In neurosurgery, the necessity of having a drainage tube is controversial. Subgaleal fluid collection (SFC) often occurs, especially in a craniotomy near the “parietal site” . This study aimed to reassess the benefit of using a prophylactic epidural drainage (ED) and non-watertight dura suture in a craniotomy near the parietal site.Methods::A retrospective review was conducted on 63 consecutive patients who underwent a craniotomy near the parietal site. The patients were divided into two groups according to different period. The deal group received ED and a non-watertight dura suture (drain group, DG), the control group that did not (non-drain group, NDG). Complications and patient recovery were evaluated and analysed.Results::Three patients (11.5%, 26) in DG and 20 patients (54.1%, 37) in NDG presented with SFC (n p 0.05). Six developed an infection in NDG (four intracranial infections, one abscess, one pulmonary infection), while none in DG ( n p > 0.05) developed infection. Three (11.5%) cases in DG and one (2.7%) case in NDG had muscle strength that improved postoperatively ( n p > 0.05). Fifteen (57.7%) in DG and 14 (37.8%) in NDG had epileptic seizures less frequently postoperatively ( n p 0.05), the maximum temperature (37.9 °C vs 38.1 °C, n p > 0.05) on 3 PODs, the postoperative hospital stay day (7.5 days vs 8.0 days, n p > 0.05), and the postoperative medicine fee (￥29762.0 vs ￥28321.0, n p > 0.05) were analysed.n Conclusion::In patients who undergo a craniotomy near the parietal site, the prophylactic use of ED and a non-watertight dura suture helps reduce SFC, infection, and control epilepsy.“,”Background::In neurosurgery, the necessity of having a drainage tube is controversial. Subgaleal fluid collection (SFC) often occurs, especially in a craniotomy near the “parietal site” . This study aimed to reassess the benefit of using a prophylactic epidural drainage (ED) and non-watertight dura suture in a craniotomy near the parietal site.Methods::A retrospective review was conducted on 63 consecutive patients who underwent a craniotomy near the parietal site. The patients were divided into two groups according to different period. The deal group received ED and a non-watertight dura suture (drain group, DG), the control group that did not (non-drain group, NDG). Complications and patient recovery were evaluated and analysed.Results::Three patients (11.5%, 26) in DG and 20 patients (54.1%, 37) in NDG presented with SFC (n p 0.05). Six developed an infection in NDG (four intracranial infections, one abscess, one pulmonary infection), while none in DG ( n p > 0.05) developed infection. Three (11.5%) cases in DG and one (2.7%) case in NDG had muscle strength that improved postoperatively ( n p > 0.05). Fifteen (57.7%) in DG and 14 (37.8%) in NDG had epileptic seizures less frequently postoperatively ( n p 0.05), the maximum temperature (37.9 °C vs 38.1 °C, n p > 0.05) on 3 PODs, the postoperative hospital stay day (7.5 days vs 8.0 days, n p > 0.05), and the postoperative medicine fee (￥29762.0 vs ￥28321.0, n p > 0.05) were analysed.n Conclusion::In patients who undergo a craniotomy near the parietal site, the prophylactic use of ED and a non-watertight dura suture helps reduce SFC, infection, and control epilepsy.