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目的:评估肝脾疏络饮联合熊去氧胆酸治疗妊娠合并乙型肝炎病毒感染胆汁淤积症的临床疗效。方法:将60例随机分成两组,治疗组30例,采用肝脾疏络饮和熊去氧胆酸治疗;对照组30例口服熊去氧胆酸治疗。结果:治疗组血清TBA、TB、ALT、AST下降明显(P<0.05),瘙痒治疗组从3.5分下降至1.6分,对照组下降缓慢从3.6分至3.1分,治疗组的顺产率为73.3%明显高于对照组20%。结论:运用肝脾疏络饮联合熊去氧胆酸明显优于单纯运用熊去氧胆酸。
Objective: To evaluate the clinical efficacy of combined treatment of liver, spleen and spleen toxin with ursodeoxycholic acid on cholestasis of pregnancy complicated with hepatitis B virus infection. Methods: Sixty cases were randomly divided into two groups. The treatment group (30 cases) was treated with Hepatic Spleen Stagnation Drink and ursodeoxycholic acid. The control group (30 cases) was treated with ursodeoxycholic acid. Results: The levels of serum TBA, TB, ALT and AST in the treatment group decreased significantly (P <0.05), the pruritus treatment group decreased from 3.5 to 1.6 and the control group decreased slowly from 3.6 to 3.1. The birth rate in the treatment group was 73.3% Obviously higher than the control group 20%. Conclusion: The combination of liver and spleen Shuluo drink with ursodeoxycholic acid was significantly better than the simple use of ursodeoxycholic acid.