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以动态心电图来判断间歇停用硝酸甘油贴敷会不会使心肌缺血增加,判断间歇疗法的疗效和安全性。 85例稳定型心绞痛和运动试验阳性的患者进行了12周的抗心绞痛治疗(多数病人同时服用其他抗心肌缺血药物),首先连续治疗3周(10mg硝酸甘油贴敷,24小时更换一次);然后随机分为两组,即连续治疗组和间歇治疗组。前组治疗不变,后组每日晚间除去贴敷10小时。分组后每例患者记录48小时动态心电图,2周后和12周结束时分别重做一次。有18例中途退出,两组各有9例。在共11194小时的动态心电图记录中
To determine the intermittent use of dynamic ECG to stop the application of nitroglycerin will increase myocardial ischemia, to determine the efficacy and safety of intermittent therapy. Eighty - five patients with stable angina pectoris and exercise test were given anti - angina pectoris for 12 weeks (most patients taking other anti - ischemic drugs at the same time). The patients were treated for three weeks continuously (10 mg nitroglycerin, once every 24 hours). Then randomly divided into two groups, namely continuous treatment group and intermittent treatment group. The former treatment unchanged, the latter group every night to remove sticking 10 hours. After grouping, each patient recorded a 48-hour Holter, and was redone at 2 and 12 weeks respectively. Eighteen patients quit midway, with 9 in each of the two groups. In a total of 11,194 hours of Holter records