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目的 :讨论采用两种姑息疗法治疗晚期食管癌患者食管狭窄程度、生存质量、生存期改善程度。方法 :经内镜留置带硅酮膜自膨式金属支架 (GRZS)治疗晚期食管癌患者 2 2例 ,其中 6例合并食管 -呼吸道瘘 ;经内镜留置导丝引导硅胶管MD - 46 10 0扩张治疗晚期食管癌患者 2 6例。结果 :该文GRZS组 2 2例治疗后食管阻塞程度由 (3.5± 0 .5 )级降至 (0 .85± 0 .35 )级 ,治疗 4周后体重增加 (7.5± 0 .5 )kg ,生存期 (10 .3±2 .1)月 ,6例食管 -呼吸道瘘 1次性治愈 ;MD组 2 6例治疗后食管梗塞程度由 (3 .15± 0 .38)级降至 (2 .15± 0 .6 9)级 ,治疗 4周后体重增加 (2 .2± 0 .7)kg ,生存期 (3 .7± 1.6 )月 ,留置GRZS在改善食管狭窄程度、生存质量、生存期均明显优于MD扩张治疗。结论 :经内镜留置带硅酮膜自膨式金属支架 (GRZS)治疗晚期食管癌是目前国际上广泛采用的姑息治疗方法 ,特别是对合并食管 -呼吸道瘘者
PURPOSE: To discuss the extent of esophageal stenosis, quality of life, and survival improvement in patients with advanced esophageal cancer treated with two palliatives. Methods: Twenty - two patients with advanced esophageal cancer treated with endoscopic silicone self - expandable metal stent (GRZS) were enrolled. Among them, 6 cases were complicated with esophageal - respiratory fistula. Silicone tube MD - 46 10 0 Dilated treatment of advanced esophageal cancer patients 26 cases. Results: The incidence of esophageal obstruction in the GRZS group decreased from (3.5 ± 0.5) to (0.85 ± 0.35) and the weight gain (7.5 ± 0.5) kg after 4 weeks of treatment (10.3 ± 2.1) months, and 6 cases of esophageal-respiratory fistula were cured in one time. The degree of esophageal infarction in 26 cases of MD group decreased from (3.15 ± 0.38) to (2 .15 ± 0. 69), after 4 weeks of treatment, the weight gain (2.2 ± 0.7) kg and survival (3.7 ± 1.6) months, indwelling GRZS in improving the degree of esophageal stricture, quality of life, Period were significantly better than MD dilation treatment. Conclusion: Endoscopic placement of self-expanding silicone stent with silicone film (GRZS) for the treatment of advanced esophageal cancer is a widely used palliative treatment in the world, especially for patients with esophageal-respiratory tract fistula