50年代以前,系统性红斑狼疮(SLF)的诊断很困难,治疗更困难,当时认为是不治之症。以后诊断水平不断提高。50年代初,开始用小剂量强的松10～30mg/d治疗SLE,症状有改善,但病人常死于狼疮性肾炎导致的肾功能衰竭。60年代初,人们开始用大 Before the 1950s, the diagnosis of systemic lupus erythematosus (SLF) was difficult and the treatment was more difficult, at the time it was considered incurable. After the diagnosis of continuous improvement. The early 50s, started with a small dose of prednisone 10 ~ 30mg / d treatment of SLE, the symptoms have improved, but patients often die of lupus nephritis caused by renal failure. In the early 60s, people began to use big