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目的探讨穴位埋线防治化疗引起的恶心呕吐的临床疗效。方法 154例晚期恶性肿瘤患者,随机分为观察组和对照组,各77例。两组患者均根据其肿瘤类型制定相应的化疗方案。对照组在每次化疗前均采用盐酸格拉司琼注射液静脉注射,观察组在首次化疗前于双侧天枢、足三里、上巨虚及中脘穴行穴位埋线防治。对比两组患者化疗后恶心呕吐的严重程度。结果观察组化疗后恶心呕吐严重程度为0度的为50.65%,显著多于对照组的19.48%,差异有统计学意义(P<0.05);观察组化疗后恶心呕吐严重程度为Ⅲ度的为10.39%,显著少于对照组的31.17%,差异有统计学意义(P<0.05)。结论穴位埋线可有效预防和减轻化疗引起的恶心呕吐症状,且操作简单、作用时间持久,具有重要的临床应用价值。
Objective To investigate the clinical efficacy of catgut embedding in preventing and treating chemotherapy-induced nausea and vomiting. Methods One hundred and fifty-four patients with advanced malignant tumor were randomly divided into observation group and control group, 77 cases each. Two groups of patients according to their tumor type to develop the appropriate chemotherapy. The control group received intravenous injection of granisetron hydrochloride before each chemotherapy. The observation group was embolized with acupoints on both sides of Tianshu, Zusanli, Shangjuxu and Zhongli points before the first chemotherapy. The severity of nausea and vomiting was compared between the two groups after chemotherapy. Results The degree of nausea and vomiting was 50.65% in observation group after chemotherapy, which was significantly higher than that in control group (19.48%, P <0.05). The severity of nausea and vomiting in observation group after chemotherapy was 10.39%, significantly less than the control group of 31.17%, the difference was statistically significant (P <0.05). Conclusion Acupoints embedding can effectively prevent and alleviate the symptoms of chemotherapy-induced nausea and vomiting, and the operation is simple, long duration of action, has important clinical value.