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甘露醇为脑脱水剂,属高渗性制剂,由肾小球排泄而肾小管不再吸收,起到利尿作用;同时又能使血浆渗透压增高,降低颅内压消除脑细胞水肿,因此在脑水肿及肾功能衰竭患儿常用。不良反应轻微。本院儿科最近遇到一例静注20％甘露醇,先后两次均引起过敏反应,现报道如下。张××,男,9个月,住院号36397。高烧,四肢抽搐,二眼上翻,口吐白沫,于1979年4月7日急诊入院。既往有中耳炎病史。体检:体温39.5℃,热性病容,前囟凹陷2×2重米,扁桃体Ⅱ度肿大,外耳道无分泌物渗出,心率160次/分,律整无杂音,肺、肝、
Mannitol is a brain dehydrator, is a hypertonic agent, excreted by the glomerular and renal tubular absorption is no longer play a diuretic effect; at the same time make the plasma osmolality increased, reduce intracranial pressure to eliminate brain cell edema, so in Brain edema and renal failure commonly used in children. Minor adverse reactions. Our hospital pediatric recently encountered a case of intravenous injection of 20% mannitol, has caused both allergic reactions, are reported below. Zhang × ×, male, 9 months, hospital number 36397. High fever, limbs convulsions, two turned up, foaming at the mouth, in April 7, 1979 emergency admission. Past history of otitis media. Physical examination: body temperature 39.5 ℃, febrile disease, anterior fontanel 2 × 2 meters, tonsil Ⅱ degree swollen, external auditory canal exudate no exudate, heart rate 160 beats / min, the whole law no noise, lung, liver,