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患者,女,24岁,因臀部、下肢无症状性水疱大疱、出血坏死性皮损,迅速扩大一周而就诊。皮损不伴任何全身不适,无生殖道和关节受累的症状和体征,未进行任何全身或局部治疗。体格检查无异常发现。除中度低补体血症,ESR、α_2-和γ球蛋白及循环免疫复合物轻度升高外,尿及全血、生化检查无异常。皮损边缘活检标本光镜和直接免疫荧光检查符合血管炎的临床诊断。尿道、宫颈、直肠及咽喉分泌物涂片革兰染色检查阴性,宫颈分泌物在Thayer-Martin培养基有淋病奈瑟菌菌落生长。其他性
Patients, female, 24 years old, due to buttocks, lower extremities asymptomatic blister hernia, hemorrhagic necrotic lesions, the rapid expansion of the week and treatment. Lesions without any general malaise, no signs and symptoms of genital tract and joint involvement, and no systemic or local treatment. No abnormal physical examination found. In addition to moderate hypocomplementemia, ESR, α_2- and γ-globulin and circulating immune complexes slightly increased, urine and whole blood, biochemical tests were normal. Percutaneous biopsy specimens by light microscopy and direct immunofluorescence were in line with the clinical diagnosis of vasculitis. Urine, cervix, rectum and throat secretions Gram stain negative, cervical secretions Neisseria gonorrhoeae colonies grow in Thayer-Martin medium. Other sex