论文部分内容阅读
L肉毒碱是一种类维生素,能够促进脂肪代谢,具有抗氧化和促进造血功能。临床主要用于调节血脂和抗贫血治疗。近来大量文献报道,L肉毒碱能够减轻组织器官缺血再灌注损伤,主要机制为:抗氧自由基损伤、促进血流灌注和能量代谢、抗凋亡作用。因此,L肉毒碱可能在防治缺血再灌注损伤的疾病中有较好的应用前景。本文就L肉毒碱抗缺血再灌注损伤作用机制研究进展作一综述。
L-Carnitine is a type of vitamin, can promote fat metabolism, with antioxidant and promote hematopoietic function. Clinical mainly for the regulation of blood lipids and anti-anemia treatment. Recently a large number of literatures reported that L-carnitine can reduce tissue ischemia-reperfusion injury, the main mechanism: antioxidant free radical damage, promoting blood flow and energy metabolism, anti-apoptotic effect. Therefore, L-carnitine may have better application prospects in the prevention and treatment of ischemia-reperfusion injury. This article reviews the progress of L-carnitine against ischemia-reperfusion injury.