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角质形成细胞(Keratinocyte,KC)具有广泛的生物学特性,对皮肤的结构和功能有着重要的影响。KC 是表皮细胞的主要组成部分,通常根据其不同的分化过程及细胞形态分为4层:基底细胞层、棘细胞层、颗粒细胞层和角质层。1967年Briggaman 等人从人皮肤中成功地分离出 KC,至今体外培养 KC 技术已有30余年的历史。随着人们对 KC 的结构功能、生长状况及生物学特性的不断了解,培养技术日趋完善,培养方法有了很
Keratinocytes (KCs) have a wide range of biological properties that have a significant impact on the structure and function of the skin. KC is the main component of epidermal cells, usually divided into four layers according to their different differentiation process and cell morphology: basal cell layer, spine cell layer, granular cell layer and stratum corneum. Briggaman et al. Successfully isolated KC from human skin in 1967 and have been cultivating KC technology in vitro for more than 30 years. As people continue to understand the structural function, growth status and biological characteristics of KC, the culture technology is maturing day by day and the cultivation methods are very good