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用过氧化氢酶电镜细胞化学和立体定量方法,观察分析慢性乙型肝炎及肝炎肝硬变时肝细胞微体的改变。分别选取慢性迁延性肝炎、非活动性肝硬变、轻度慢性活动性肝炎、重度慢性活动性肝炎、活动性肝硬变及正常对照组标本各5例。结果表明,慢性迁延性肝炎和非活动性肝硬变时微体的体密度无改变,而轻、重度慢性活动性肝炎及活动性肝硬变的微体数密度、体密度均不同程度地增加,是慢性肝病活动性的表现。微体增多可作为慢性活动性肝炎与慢性迁延性肝炎之间的区分和肝硬变活动性判定的指标。文章提出病毒性肝炎时微体增多是肝细胞针对毒氧素进行解毒的慢性代偿性反应.
Using catalase and cytochemistry and stereotactic method to observe the change of hepatocyte microcyst in chronic hepatitis B and hepatitis cirrhosis. Five cases of chronic persistent hepatitis, inactive cirrhosis, mild chronic active hepatitis, severe chronic active hepatitis, active cirrhosis and normal control group were selected respectively. The results showed that there was no change in the density of micromembranes in patients with chronic persistent hepatitis and inactivation of cirrhosis, while the density of microdam and body density of mild to severe chronic active hepatitis and active cirrhosis increased to varying degrees , Is the manifestation of chronic liver disease activity. Increased micro-organisms can be used as an indicator of the distinction between chronic active hepatitis and chronic persistent hepatitis and cirrhosis activity determination. The article proposes that the increase of micro-bodies in viral hepatitis is a chronic compensatory response of hepatocytes to detoxification of toxicoxins.