以绒毛为材料直接制备染色体,为孕早期产前诊断开辟了广阔前景。但因其方法不稳定为诊断分析带来困难。关于其方法的研究有很多报道,而再现性欠佳,本实验针对染色体分散差及发毛问题,从方法学上做了初步探讨,现报告如下。 材料和方法 一、对象 取30名人工流产妇女的绒毛组织20mg,将其分成二份,孕龄为6～10周。 二、方法 1.对照组 将绒毛组织用D—Hank’s液漂洗 Chromosome as a material directly prepared chromosomes for prenatal diagnosis of early pregnancy has opened up a broad prospect. However, because of its instability, diagnostic analysis brings difficulties. There are a lot of reports about its method, but its reproducibility is not good. In this experiment, the method of chromosomal dispersion and hair loss is poor. Materials and methods First, the object to take 30 artificial abortion women villi tissue 20mg, divided into two, gestational age of 6 to 10 weeks. Second, the method 1. Control group villi tissue rinse with D-Hank’s solution