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目的探讨小儿哮喘与肺炎支原体感染的临床相关性,提高小儿哮喘的治疗效果。方法收集住院治疗的120例支气管感染患儿与150例支气管感染伴哮喘患儿,通过血清学检查支原体感染情况,并汇总分析。将检查出的哮喘伴肺炎支原体感染患儿62例随机分为对照组与观察组,对照组给予抗生素、激素及支气管扩张剂治疗,观察组在此基础上加阿奇霉素序贯治疗,1个月后观察治疗效果,2个月后随访复发率。结果支气管感染组与支气管感染伴哮喘组在支原体感染方面比较,差异有统计学意义(P<0.01);对照组与观察组经治疗后,治愈率比较差异有统计学意义(P<0.05),治愈后复发率比较差异有统计学意义(P<0.01)。结论小儿发生哮喘时,应加强肺炎支原体的实验室检查,伴有肺炎支原体感染时,阿奇霉素序贯治疗能提高治愈率,有效控制复发率。
Objective To explore the clinical correlation between pediatric asthma and mycoplasma pneumoniae infection and to improve the therapeutic effect of pediatric asthma. Methods A total of 120 children with bronchial infection and 150 children with bronchial asthma who were hospitalized were enrolled in this study. Mycoplasma infection was detected by serology and analyzed. Sixty-two children with asthma and mycoplasma pneumoniae infection were randomly divided into control group and observation group. The control group was treated with antibiotics, hormones and bronchodilators. The observation group was treated with azithromycin sequential treatment. One month later Observed the effect of treatment, follow-up after 2 months the recurrence rate. Results The bronchial infection and bronchial infection with asthma in the mycoplasma infection, the difference was statistically significant (P <0.01); the control group and the observation group after treatment, the cure rate was significantly different (P <0.05) The recurrence rate after cure was significantly different (P <0.01). Conclusions In asthmatic children, we should strengthen the laboratory examination of mycoplasma pneumoniae. Sequential azithromycin treatment can improve the cure rate and effectively control the recurrence rate when mycoplasma pneumoniae is infected.