论文部分内容阅读
[目的]观察小青龙汤联合西药治疗小儿哮喘疗效。[方法]使用随机平行对照方法,将172例住院患者按掷骰子法简单随机分为两组。对照组86例抗生素、氨茶碱、糖皮质激素。治疗组86例小青龙汤(小青龙汤,麻黄9g,干姜、桂枝各6g,细辛5g,白芍、五味子、法半夏、毛桃根、射干各9g,甘草炙5g,僵蚕、款冬花各9g,紫菀6g,葶苈子9g,熟地6g,生龙牡、桑白皮、大枣各9g)1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、免疫球蛋白(Ig G、Ig A、Ig M、Ig E)、用力肺活量(FVC)、血清白细胞介素4(IL-4)、γ干扰素(INF-γ)、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效54例,有效27例,无效5例,总有效率94.19%。对照组显效41例,有效31例,无效14例,总有效率83.72%。治疗组疗效优于对照组(P<0.05)。症状、体征积分两组均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.05,P<0.01)。症状改善时间治疗组改善短于对照组(P<0.01)。[结论]小青龙汤联合西药治疗小儿哮喘疗效满意,无严重不良反应,值得推广。
[Objective] To observe the effect of Xiao Qing Long Decoction combined with Western medicine in treating pediatric asthma. [Methods] Using randomized parallel control method, 172 inpatients were randomly divided into two groups according to the dice method. The control group of 86 cases of antibiotics, aminophylline, glucocorticoid. Treatment group, 86 cases of Xiao Qinglong Decoction (Xiao Qinglong Decoction, ephedra 9g, ginger, cassia 6g, asarum 5g, white peony root, Schisandra, France pinellia, peach root, Shegan 9g, licorice Sunburn 5g, Coltsfoot flower 9g, Aster 6g, razor clam 9g, Rehmannia 6g, Health Longmu, Morus alba, jujube 9g) 1 dose / d, decoction 200m L, morning and evening oral; Western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. The clinical symptoms, immunoglobulin (Ig G, Ig A, Ig M, Ig E), forced vital capacity (FVC), serum interleukin 4 (IL-4), IFN- γ and adverse reactions were observed. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group markedly effective in 54 cases, effective in 27 cases, ineffective in 5 cases, the total effective rate was 94.19%. In the control group, 41 cases were markedly effective, 31 cases were effective, 14 cases were ineffective, and the total effective rate was 83.72%. The treatment group was better than the control group (P <0.05). Symptoms and signs were improved in both groups (P <0.05, P <0.01), and the treatment group improved better than the control group (P <0.05, P <0.01). The symptom improvement time in treatment group improved shorter than that in control group (P <0.01). [Conclusion] Xiaoqinglong Decoction combined with Western medicine is effective in treating children with asthma without serious adverse reactions and is worth promoting.