目前在全世界范围内,冠心病已成为第一位的死亡原因。骨髓间充质干细胞(BMSCs)具有自我复制能力,可以向多种细胞分化,已有大量实验研究了它的分离、培养和体外诱导为心肌样细胞的生物学特性。近年来,BMSCs移植治疗冠心病的动物实验和临床研究均显示出较好的效果。BMSCs移植正成为治疗缺血性心脏病的一种崭新技术,具有广阔的发展前景。 Coronary heart disease has become the first cause of death in the world. Bone marrow mesenchymal stem cells (BMSCs) have the ability of self-replication and can differentiate into many kinds of cells. A large number of experimental studies have been made about the biological characteristics of their differentiation, culture and in vitro induction into cardiomyocyte-like cells. In recent years, BMSCs transplantation in the treatment of coronary heart disease in animal experiments and clinical studies have shown good results. BMSCs transplantation is becoming a new technology for the treatment of ischemic heart disease, with broad prospects for development.